Table 3 Peak plasma concentrations and time to reach peak for each subject
Group A (n = 15) (300 mg bupivacaine) | Group B (n = 14) (200 mg bupivacaine) | ||||
|---|---|---|---|---|---|
Subject | Cmax (ng/mL) | Tmax (h) | Subject | Cmax (ng/mL) | Tmax (h) |
1a | 815.0 | 1.0 | 1b | 537.7 | 3.4 |
2a | 337.0 | 3.3 | 2b | 377.6 | 1.0 |
3a | 360.9 | 1.0 | 3b | 491.1 | 1.0 |
4a | 875.4 | 2.8 | 4b | 804.1 | 3.9 |
5a | 481.7 | 1.0 | 5b | 682.3 | 3.7 |
6a | 716.3 | 1.0 | 6b | 636.5 | 2.9 |
7a | 727.8 | 3.5 | 7b | 446.3 | 3.3 |
8a | 1572.9 | 3.4 | 8b | 324.5 | 3.4 |
9a | 462.9 | 4.2 | 9b | 435.2 | 3.7 |
10a | 350.0 | 3.4 | 10b | 562.3 | 3.8 |
11a | 854.4 | 1.0 | 11b | 712.5 | 4.5 |
12a | 298.4 | 4.1 | 12b | 573.2 | 1.0 |
13a | 425.6 | 1.0 | 13b | 392.0 | 3.5 |
14a | 296.1 | 3.4 | 14b | 503.8 | 2.4 |
15a | 291.5 | 4.6 | |||
Mean | 591.1 | 2.6 | Mean | 534.2 | 3.0 |
SD | 347.7 | 1.4 | SD | 138.2 | 1.2 |