Table 2 Plasma bupivacaine concentrations following bilateral adductor canal blocks combined with periarticular infiltrations
Group A (n = 15) (300 mg bupivacaine) | Group B (n = 14) (200 mg bupivacaine) | P | |
|---|---|---|---|
Plasma concentrations (ng/mL) | |||
60 min after bilateral ACB | 446.5 (222.8) | 391.8 (118.4) | 0.421 |
Before PAI of 1st knee | 360.4 (193.6) | 297.2 (117.4) | 0.301 |
40 min after PAI of 1st knee | 369.3 (282.1) | 291.1 (133.5) | 0.354 |
15 min after PAI of 2nd knee | 378.1 (249.4) | 333.5 (143.6) | 0.563 |
30 min after PAI of 2nd knee | 355.6 (175.9) | 348.8 (171.5) | 0.917 |
45 min after PAI of 2nd knee | 510.3 (286.5) | 451.0 (164.7) | 0.504 |
60 min after PAI of 2nd knee | 483.1 (309.0) | 417.8 (162.4) | 0.487 |
90 min after PAI of 2nd knee | 499.2 (351.3) | 501.6 (154.9) | 0.982 |