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Table 3 Clinical outcome comparison after TKA between PD and control patients

From: The effect of Parkinson’s disease on total knee arthroplasty: a systematic review and meta-analysis

 

Year

Author

Preoperation (PD)

Preoperation (Control)

Postoperation (PD)

Postoperation (Control)

Others

Acta Orthop. Belg

2013

Craig

KSS 30.5

ROM 95 (30–120)

KSS 32.5

ROM 88 (46–125)

KSS 91

ROM 100 (70–125)

KSS 88

ROM 110 (10–125)

Pain score, ROM were comparable in both group and no functional improvement in PD at postoperative 1 year

J Arthroplasty

2017

Rodon

Functional SF-12 score

27.7 ± 1.06

Functional SF-12 score 32.9 ± 1.14

Functional SF-12 score 37.1 ± 1.67

10 year survival: 66.2%

Functional SF-12 score 44.1 ± 1.27

Improvement in functional scores was significantly less in patients with PD compared to controls (p = 0.003)

Patients with PD who received TKA demonstrated decreased survivorship than their matched controls (p = 0.0045)

J arthroplasty

2018

Wong

  

OKS 38.3 ± 7.2

ΔOKS 18.6 ± 6.8

ROM 113.2 ± 8.3

ΔROM 12.34 ± 5.4

OKS 40.2 ± 6.5 (p = 0.34)

ΔOKS 16.5 ± 8.1 (p = 0.45)

ROM 114.4 ± 9.8 (p = 0.62)

ΔROM 12.2 ± 4.5 (p = 0.96)

 

J Orthop Surg Res

2019

Xiao

KSS score

Pain 21.11 ± 9.63

ROM 22.22 ± 1.86

Stability 17.89 ± 2.00

Total 61.22 ± 9.66

KSFS 39.72 ± 6.52

SF-12 (PCS) 15.61 ± 3.55

SF-12 (MCS) 20.28 ± 3.49

WOMAC pain 8.39 ± 2.55

WOMAC stiffness 2.94 ± 1.30

WOMAC function 38.00 ± 6.73

ROM: 111.11 ± 9.32

 

KSS score

Pain 43.61 ± 12.10 (p < 0.01)

ROM 23.61 ± 1.61 (p < 0.01)

Stability 24.11 ± 1.18 (p < 0.01)

Total 91.33 ± 12.57 (p < 0.01)

KSFS 58.06 ± 31.11 (p = 0.02)

SF-12 (PCS) 20.17 ± 5.08 (p < 0.01)

SF-12 (MCS) 24.00 ± 5.16 (p = 0.02)

WOMAC pain 3.39 ± 4.55 (p < 0.01)

WOMAC stiffness 0.61 ± 1.50 (p < 0.01)

WOMAC function 26.44 ± 15.24 (p < 0.01)

ROM: 118.33 ± 8.22 (p < 0.01)

 

HY I, II stage show better result (KSS total, WOMAC, pain, function) than HY, III, IV and SF-12, WOMAC score correlated with HY stage (p < 0.01)

AOTS

2020

Veronica

KSS 32 (20–45)

KSFS 34 (28–52)

VAS 8

ROM 97

 

KSS 71 (50–81)

KSFS 59 (25–76)

VAS 5

ROM 116

  

J Arthroplasty

2020

Goh

KSKS 36.5 ± 19.3

KSFS 39.1 ± 24.9

OKS 20.5 ± 10.5

SF-36 PCS 28.8 ± 8.9

SF-36 MCS 45.5 ± 11.5

ROM 108.0 ± 17.7

KSKS 33.1 ± 16.3

KSFS 34.8 ± 25.3

OKS 19.9 ± 9.2

SF-36 PCS 29.3 ± 10.8

SF-36 MCS 47.0 ± 11.6

ROM 105.4 ± 29.2

KSKS 82.0 ± 16.6

KSFS 48.2 ± 26.6

OKS 34.6 ± 10.0

SF-36 PCS 39.6 ± 11.3

SF-36 MCS 50.7 ± 12.2

ROM 110.4 ± 15.1

KSKS 81.9 ± 18.5 (p = 0.978)

KSFS 67.2 ± 21.4 (p < 0.001)

OKS 39.0 ± 8.7 (p = 0.014)

SF-36 PCS 43.5 ± 13.4 (p = 0.092)

SF-36 MCS 54.1 ± 9.9 (p = 0.109)

ROM 112.5 ± 17.6 (p = 0.490)

 

J Orthop Sci

2020

Ergin

KSS 45.4 ± 16.8

ROM 93.9 ± 17.0

Flexion contracture 8.85 ± 7.12

KSS 38.8 ± 11.5

ROM 100.4 ± 14.6

Flexion contracture 7.41 ± 4.84

KSS 85.6 ± 7.60

ROM 99.5 ± 9.37

KSS 85.6 ± 10.0

ROM 109.2 ± 10.2

Similar outcomes compared with general population despite disease severity and progression

Mean increase in KSS and ROM values were significantly higher for high-grade patients (p < 0.05)

High-grade PD: similar outcome

Int Orthop

2021

Baek

KSS 36.8 ± 5.4

Functional score 35.5 ± 4.4

KSS 37.1 ± 4.8

Functional score 35.9 ± 6.7

KSS 60.0 ± 24.5

Functional score 57.5 ± 29.7

Survival rate: 89.7%

KSS 80.7 ± 13.1

Functional score 81.5 ± 17.4

Survival rate: 98.3%

 

BMC Musculoskeletal Dis

2022

Y. Zong

EQ-pain and discomfort

2.19 ± 0.60

PDQ-function

57.8 ± 26.3

EQ-pain and discomfort

2.40 ± 0.57

PDQ-function

46.7 ± 21.6

EQ-pain and discomfort

2.37 ± 0.49

PDQ-function

53.3 ± 21.0

EQ-pain and discomfort

1.92 ± 0.58

PDQ-function

32.8 ± 24.3

 
  1. KSS: knee society score; KSFS: knee society functional score; KSKS: knee society knee score; MCS: mental component summary; OKS: Oxford knee score; PCSL physical component summary; PD: Parkinson’s disease; ROM: range of motion; TKA: total knee arthroplasty; VAS: visual analog scale; WOMAC: Western Ontario and McMaster Universities Osteoarthritis Index; EQ: Euro QOL; PDQ: Pain and Disability Questionnaire