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Table 1 Summary of the literature evaluating the use of hUCB-MSC

From: Past, present, and future of cartilage restoration: from localized defect to arthritis

 

Patients (n)

Follow-up (years)

Staging

Clinical score

Imaging and second look

Key features of the study

Park et al.

7

7

ICRS4

VAS, IKDC

MRI

Histological evaluation

Na et al.

14

1

ICRS3B

IKDC, KSS, WOMAC

ICRS CRA

Concomitant HTO

Better result compared with BMAC (25 cases)

Lim et al.

73

5

ICRS4

VAS, WOMAC, IKDC

 

Better result compared with microfracture

Song et al.

25

2

ICRS4

VAS, IKDC, WOMAC

ICRS CRA

Concomitant HTO

Song et al.

128

2

ICRS4

VAS, IKDC, WOMAC

MRI (N = 34)

Better result for LFC, trochlea compared with MFC

Song et al.

125

3

ICRS4

VAS, WOMAC, IKDC

ICRS CRA

Concomitant HTO