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Table 4 Effectiveness of iron supplementation according to the route of administration

From: Effectiveness of iron supplementation in the perioperative management of total knee arthroplasty: a systematic review

Author Year Journal Transfusion indication Transfusion rate_IV
(N, %)
Transfusion rate_Oral
(N, %)
Hb_IV (g/dL) Hb_Oral (g/dL)
Biboulet et al. [22] 2018 Anesthesiology     Pre-OP (14.9)
POD 1D (12.6)
POD 3D (12.6)
POD 5D (13.4)
Pre-OP (13.9)
POD 1D (12.2)
POD 3D (11.6)
POD 5D (12.3)
Bisbe et al. [23] 2014 Br J Anaesth Hb < 8 g/dL or acute anemia symptoms 3 (5%) 2 (3.2%) Pre-OP (13.6 ± 0.9)
POD 1D (10.5 ± 1.0)
POD 4D (9.7 ± 1.3)
POD 30D (11.5 ± 1.2)
Pre-OP (13.6 ± 0.9)
POD 1D (10.5 ± 1.0)
POD 4D (9.7 ± 1.1)
POD 30D (11.0 ± 1.1)
Gonzalez-Porras et al. [29] 2009 Transfus Med Hb < 7 g/dL for healthy patients
Hb < 8 g/dL for poor tolerance of anemiaHb < 9 g/dL for cardiac or respiratory failure
10 (20.4%) 29 (20%) Pre-OP (13.3 ± 0.2)
POD discharge (10.3 ± 0.8)
Pre-OP (14.3 ± 0.8)
POD discharge (10.7 ± 0.1)
  1. D day, OP operation, POD post-operation day, Hb hemoglobin