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Table 5 Reported outcomes – Knee injury and Osteoarthritis Outcome Score (KOOS) and numerical rating score (NRS) following intraarticular injection of autologous protein solution/autologous conditioned serum (ACS/APS)

From: Autologous cell-free serum preparations in the management of knee osteoarthritis: what is the current clinical evidence?

Author and yearStudy patientsAge at presentation
Mean (± SD)/median (range)
Follow-up (months)
Mean (± SD)/median (range)
Outcome measureBaselinePost procedure
Score
Mean (± SD)/median (range)
Time point(s) (weeks/months)Score
Mean (± SD)/median (range)
Kon et al. 2018 [22]4657 (41–68)12 (± NR)KOOS39.9 (± NR)12 monthsNR
Hix et al. 2017 [20]1058.8 (± 9.5)12 (± NR)KOOS36.9 (± 16.2)12 months79.7 (± 16.2)
Rutgers et al. 2015 [36]2050 (34–70)12 (± NR)KOOS49.45 (± 11.46)12 months51.20 (± 13.09)
Hix et al. 2017 [20]1058.8 (± 9.5)12 (± NR)NRS5.9 (± 1.9)12 months1.6 (± 1.6)
Garcia-Escudero et al. 2015 [35]11859 (34–81)24 (± NR)NRS8.10 (± NR)12 months3.03 (± NR)
  1. NR Not reported