Table 5 Reported outcomes – Knee injury and Osteoarthritis Outcome Score (KOOS) and numerical rating score (NRS) following intraarticular injection of autologous protein solution/autologous conditioned serum (ACS/APS)
Author and year | Study patients | Age at presentation Mean (± SD)/median (range) | Follow-up (months) Mean (± SD)/median (range) | Outcome measure | Baseline | Post procedure | |
|---|---|---|---|---|---|---|---|
Score Mean (± SD)/median (range) | Time point(s) (weeks/months) | Score Mean (± SD)/median (range) | |||||
Kon et al. 2018 [22] | 46 | 57 (41–68) | 12 (± NR) | KOOS | 39.9 (± NR) | 12 months | NR |
Hix et al. 2017 [20] | 10 | 58.8 (± 9.5) | 12 (± NR) | KOOS | 36.9 (± 16.2) | 12 months | 79.7 (± 16.2) |
Rutgers et al. 2015 [36] | 20 | 50 (34–70) | 12 (± NR) | KOOS | 49.45 (± 11.46) | 12 months | 51.20 (± 13.09) |
Hix et al. 2017 [20] | 10 | 58.8 (± 9.5) | 12 (± NR) | NRS | 5.9 (± 1.9) | 12 months | 1.6 (± 1.6) |
Garcia-Escudero et al. 2015 [35] | 118 | 59 (34–81) | 24 (± NR) | NRS | 8.10 (± NR) | 12 months | 3.03 (± NR) |