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Table 3 Results of univariate analysis for factors related to DAIR failure in patients with acute hematogenous PJI

From: Worse outcome of debridement, antibiotics, and implant retention in acute hematogenous infections than in postsurgical infections after total knee arthroplasty: a multicenter study

 

Success (n = 48)

Failure (n = 19)

p-Value

Age (years)

74.1 ± 9.4

72.6 ± 8.8

0.556

Female

39 (81.3)

16 (84.2)

1.000

BMI (kg/m2)

28.1 ± 5.4

26.6 ± 3.5

0.191

Diabetes

28 (58.3)

11 (57.9)

0.974

CCI

3.7 ± 1.6

3.5 ± 0.9

0.554

Symptom duration (days)

7.6 ± 7.8

9.8 ± 9.1

0.326

Operation

   

 Primary

44 (92)

15 (79)

0.209

 Revision

4 (8)

4 (21)

Implant age (Month)*

17.5 (8.8–47.8)

12.0 (7.0–38.0)

0.313

Preoperative CRP

12.3 ± 8.8

16.9 ± 13.6

0.186

Type of organism

   

 Staphylococcus aureus

10 (20.8)

5 (26.3)

0.035

 Antibiotic-resistant (MRSA, MRSE)

5 (10.4)

4 (21.1)

 Streptococcus

13 (27.1)

2 (10.5)

 Enterococcus

1 (2.1)

0 (0.0)

 Candida

0 (0.0)

1 (5.3)

 Gram negative

7 (14.6)

2 (10.5)

 Polymicrobial

0 (0.0)

3 (15.8)

 Culture negative

12 (25.0)

2 (10.5)

  1. Data are presented as mean and standard deviation or number and percentage in parentheses
  2. DAIR debridement, antibiotics, and implant retention, PJI periprosthetic joint infection, n number, CCI Charlson comorbidity index, CRP C-reactive protein, MRSA methicillin-resistant Staphylococcus aureus, MRSE methicillin-resistant Staphylococcus epidermidis
  3. *Data of implant age are presented as median and interquartile range in parentheses