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Table 2 Results of univariate analysis for factors related to DAIR failure in overall patients

From: Worse outcome of debridement, antibiotics, and implant retention in acute hematogenous infections than in postsurgical infections after total knee arthroplasty: a multicenter study

 

Success

(n = 78)

Failure

(n = 23)

p-value

Age (years)

74.2 ± 8.6

73.4 ± 8.2

0.679

Female

63 (80.8)

18 (78.3)

0.772

BMI (kg/m2)

27 ± 4.9

26 ± 3.5

0.381

Diabetes

37 (47.4)

11 (47.8)

0.974

CCI

3.7 ± 1.4

3.5 ± 0.8

0.577

Symptom duration (days)

7.3 ± 7.6

9.3 ± 8.4

0.267

Operation

   

 Primary

71 (90)

19 (83)

0.462

 Revision

8 (10)

4 (17)

Implant age (Month)*

8.0 (1.0–33.0)

11.0 (5.0–35.5)

0.545

Preoperative CRP

11.6 ± 8.5

16.6 ± 12.5

0.082

Type of organism

   

 Staphylococcus aureus

15 (19.5)

6 (26.1)

0.139

 Antibiotic resistant (MRSA, MRSE)

12 (15.6)

5 (21.7)

 Streptococcus

17 (22.1)

3 (13.0)

 Enterococcus

2 (2.6)

0 (0.0)

 Candida

2 (2.6)

1 (4.3)

 Gram negative

8 (10.4)

3 (13.0)

 Polymicrobial

1 (1.3)

3 (13.0)

 Culture negative

20 (26.0)

2 (8.7)

Type of infection

   

 Acute postsurgical PJI

30 (38)

4 (17)

0.060

 Acute hematogenous PJI

48 (62)

19 (83)

  1. Data are presented as mean and standard deviation or number and percentage in parentheses
  2. DAIR debridement, antibiotics, and implant retention; PJI periprosthetic joint infection, n number, CCI Charlson comorbidity index, CRP C-reactive protein, MRSA methicillin-resistant Staphylococcus aureus, MRSE methicillin-resistant Staphylococcus epidermidis
  3. *Data of implant age are presented as median and interquartile range in parentheses