Table 2 Characteristics of the platelet-rich plasma injection used in each trial

Scott et al. 2019 [16]

Angel Cytomedix System

(ABS-10060; Arthrex Inc, USA)

52 ml venous blood resulted in 3.5 ml PRP

Citrate dextrose

Solution A

NR

LR-PRP (details not reported)

LP-PRP (Details not reported)

230 × 10³ (LR-PRP);

227 × 10³ (LP-PRP)

LR-PRP: 3.8 fold

LP-PRP: 3.0 fold

NR

Dragoo et al. 2014 [17]

GPS III (Biomet Inc, Warsaw, IN, USA) PRP Kit

55 ml venous blood resulted in 6 ml LR-PRP

NR

NR

LR-PRP (details not reported)

NR

NR

NR

Kaux et al. 2019 [18]

Apheresis machine (CCM TEC and Kit CS5, Fresenius-Kabi, Bad-I Iomburg, Germany)

6 ml PRP was prepared and injected

NR

NR

LP-PRP (details not reported)

850 × 10³ (LP-PRP)

NR

Calcium chloride

Filardo et al. 2010 [19]

NR

150 ml venous blood resulted in 20 ml PRP

NR

Double centrifugations; 1800 RPM for 15 min followed by 3500 RPM for 10 min

NR

NR

6 fold

10% Calcium chloride

Rodas et al. 2021 [20]

NR

36 ml venous blood resulted in 6 ml PRP

Citrate

Single centrifugation; 1800 RPM for 8 min

LP-PRP (details not reported)

563 × 10³/mm³

LP-PRP: 2.5 fold

5% Calcium chloride

Vetrano et al. 2013 [15]

The Recover Platelet Separation Kit (Kaylight Ltd, Israel)

10 ml venous blood resulted in 6–7 ml PRP

Acid-citrate-dextrose

Single centrifugation; 1500 RPM for 10 min

NR

0.89–1.1 × 10⁹ ml

3–5 fold

NR

Abdelbary et al. 2018 [21]

Arthrex Double Syringe System (Arthrex Inc, USA)

15 ml venous blood resulted in 6 ml of PRP

NR

Single centrifugation, 1700 RPM for 6 min

NR

NR

NR

NR

Abate et al. 2018 [22]

Regen Lab A-PRP Kit (Regenlab, Switzerland)

8 ml venous blood resulted in 6 ml of PRP

Citrate

Single centrifugation, 3400 RPM for 5 min

LP-PRP (leucocytes nil; details not reported)

NR

1.6 fold

Nil