From: Is there an optimal age for total knee arthroplasty?: A systematic review
Author | Journal | Year | Number | Age (years) | Result |
---|---|---|---|---|---|
No difference | |||||
 Sveikata [33] | Geriatr Orthop Surg Rehabil | 2017 | 314 | < 75, ≥ 75 | Post operation 1 year: no difference in pain (P = 0.592), stiffness (P = 0.729), or function (P = 0.082) according to WOMAC and SF-12 physical (P = 0.082) and mental (P = 0.559) health score |
 Escobar [31] | J Eval Clin Pract | 2017 | 492 |  | No difference between minimal clinically important difference (MCID)/patient acceptable symptom state (PASS) (P = 0.5) |
 Lizaur-Utrilla [35] | Knee Surg Sport Traumatol Arthrosc | 2016 | ≤ 55: 61 60–70: 61 | ≤ 55, 60–70 | Post operation 5 years, there were no significant differences between groups in KSS knee or function, WOMAC pain or function, or SF-12 physical or mental. However, there were better results in younger patients for KSS function (P = 0.018), WOMAC function (P = 0.028), SF-12-physical (P = 0.001) and SF-12-mental (P = 0.035), although clinically relevant |
 Maempel [40] | Acta Orthop | 2015 | 3144 | < 75, 75–80, > 80 | Post operation 5 years: all groups showed similar substantial improvements in AKS, which were maintained (all P < 0.001) |
 Kuo [44] | J Orthop Surg Res | 2014 | 1024 | < 80, ≥80 | Both groups (≥ 80, < 80) had improved in the KSS (≥ 80: 86, < 80: 88), KSFS (≥ 80: 87, < 80: 89), WOMAC (≥ 80: 15.0, < 80: 14.6) scores |
 Hamilton [47] | BMJ Open | 2013 | 4709 |  | Median age of satisfied group is 70.3 and unsatisfied group is 70.0 (P = 0.829) |
 Kennedy [48] | Clin Orthop Rel Res | 2013 | ≥80: 438 < 80: 2754 | < 80, ≥80 | There was no difference in pain scores at 3, 5, and 10 years between the ≥ 80 years group and < 80 years group. The KSS was comparable between groups at year 5, but the KSFS was lower in the octogenarians |
 William [50] | Bone Joint J | 2013 | 2456 | < 55 55–64, 65–74, 75–84, ≥ 85 | Postoperative scores were comparable across age groups, but a linear trend for greater postoperative improvement in OKS and EQ-5D was seen with decreasing age (P < 0.033) |
 Clement [53] | Bone Joint J | 2011 | 677 | < 80, ≥ 80 | Post operation 1 year: no significant difference was observed between the groups in the mean improvement in OKS (95% CI − 0.65 to 2.94, P = 0.16) |
Difference | |||||
 Pitta [25] | J Arthroplast | 2019 | 3693 |  | For the KOOS pain, KOOS activity, and LEAS outcomes, the divergence point occurred at age 68 years. For the KOOS symptom outcomes, the divergence point occurred at age 70 years. |
 Elmallah [34] | J Knee Surg | 2016 | 278 | < 55, 55–74, > 74 | For KSS objective, patiemts 75 years and older had the highest mean score at final follow up (97 points). In KSS function, the < 55-years group had highest scores at 2-year (90 vs. 87 vs. 75 points) and 5-year follow up (96 vs. 88 vs. 72 points). For SF-36 and LEAS, the cohorts 75 years and older had the lowest mean scores at various time points. In the mental component, those < 55 years had the lowest scores postoperatively |
Older better | |||||
 Townsend [29] | J Knee Surg | 2018 | 356 | < 50, 50–59, 60–69, 70–79, > 79 | Postoperative WOMAC and overall, pain, and function OKS significantly differed among the age groups (P  < 0.05), with patients younger than 60 years reporting the worst scores in the postoperative time period. Older patients reported better preoperative overall, pain, and function scores and greater post-TKA outcomes than younger patients |
 Merle-Vincent [54] | Joint Bone Spine | 2011 | 264 | ≤ 70, > 70, | Age older than 70 years at surgery was associated with a higher satisfaction rate (odds ratio of age ≥ 70 years is 3.9 [1.1–14.3]; P = 0.038) |
Younger better | |||||
 Murphy [14] | Bone Joint J | 2018 | 2838 | < 80, ≥ 80 | SF-12 PCS, coefficient of ≥ 80-group is − 4.46 (− 6.18, − 2.73), P < 0.001 |
 KJ Oh [26] | Aging Clin Exp Res | 2018 | 79 | 65–70, ≥ 80 | The octogenarian patient group had significantly inferior outcomes for WOMAC and SF-36 score compared to the sexagenarian patient group (P = 0.009 and P = 0.022, respectively) |
 Naylor [28] | Arthritis Care Res | 2018 | 1289 |  | Post operation 3 years: younger age (P = 0.0018) was significantly associated with regular physical activity |
 Razak [36] | J Bone Joint Surg Am | 2016 | 3062 |  | Younger age KSS predicted a good outcome at 5 years (OKS: OR of age is 2.66 (2.61–2.71), SF-36 PCS: OR of age is 2.64 (2.59–2.67)) |
 Singh [57] | Osteoarthr Cartil | 2010 | 7139 | 61–70, 71–80, > 80 | Significantly predictors of overall moderate–severe activity limitation 2-years post-TKA was age 71–80 (OR: 2.1 [1.5, 2.8]) and age > 80 (OR: 4.1 [2.7, 6.1]) vs, age ≤ 60 years, and 5 years post-TKA was age 71–80 (OR: 2.4 [1.7, 3.5]) and age > 80 (OR: 4.7 [2.8, 7.9]) vs. age ≤ 60 years |
Extreme age | |||||
 Extreme old age | |||||
  Skinner [37] | Ann R Coll Surg Eng | 2016 | 67 | 70–79, 90–99 | For preoperative OKS no significant difference between nonagenarians and control group |
 Extreme young age | |||||
  Lange [27] | J Arthroplast | 2018 | 1058 | 18–55, 65–75 | Distribution of satisfaction responses was shifted toward greater satisfaction in older patients (P < 0.001). Younger patients reported greater knee-related dysfunction and higher activity levels preoperatively and postoperatively (P = 0.0002) |
  Haynes [32] | Knee | 2017 | ≤ 55: 82 65–75: 85 | ≤55, 65–75 | The younger patient cohort reported substantially lower preoperative clinical outcome scores. WOMAC pain (12.1 points, P < 0.01), and WOMAC physical function. (6.9 points, P < 0.01) improvement was noted; however, WOMAC pain score remained lower among the younger patient cohort |
  Clement [19] | Arch Arthop Trauma Surg | 2018 | 2589 | < 55, 55 ≤ | The younger age group was twice as likely to be dissatisfied with their overall outcome and pain relief, with only 83% and 85% being satisfied compared to 92% and 91% in the older age group, respectively |