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Table 1 Baseline demographics of the patients and information on blood transfusions

From: Prospective randomized trial comparing efficacy and safety of intravenous and intra-articular tranexamic acid in total knee arthroplasty

Covariates

Group A (IA 20 mg/kg)

(N = 50)

Group B (IA 2 g/kg)

(N = 50)

Group C (IV 20 mg/kg)

(N = 50)

P value#

Age

67.40 (50–79)

65.82 (54–83)

66.58 (50–81)

0.40

Sex (male:female)

13:37

7:43

14:36

0.22

Side (left:right)

26:24

23:27

26:24

0.86

Height (cm)

154.97 (145–174)

154.44 (138–172)

156.02 (142–171)

0.89

Weight (kg)

68.20 (53–98)

67.76 (54–95)

68.13 (48–99)

0.96

BMI (kg/m2)

28.42 (21–40)

28.36 (22–37)

27.99 (20–42)

0.83

ASA

3:37:9

10:34:4

8:37:4

0.15

Length of stay (days)

8.88 (4–34)

7.96 (5–15)

8.70 (5–45)

0.53

Baseline hemoglobin (g/dL)

13.73 (12–16)

13.39 (12–15)

13.41 (12–17)

0.17

Day 0 hemoglobin (g/dL)

12.27 (10–15)

12.06 (10–14)

12.17 (10–15)

0.78

Day 2 hemoglobin (g/dL)

10.60 (8–15)

10.61 (9–14)

10.73 (9–13)

0.74

Day 5 hemoglobin (g/dL)

10.59 (8–13)

10.57 (9–13)

10.69 (8–13)

0.76

Baseline platelet

236.62 (132–378)

225.50 (129–335)

241.68 (137–379)

0.34

Day 0 platelet

212.28 (108–348)

201.28 (111–314)

218.34 (121–339)

0.20

Day 2 platelet

184.04 (109–303)

173.42 (103–291)

193.22 (110–397)

0.11

Day 5 platelet

275.64 (155–458)

263.76 (144–408)

282.62 (162–519)

0.34

Baseline hematocrit

0.41 (0.36–0.48)

0.40 (0.36–0.46)

0.41 (0.36–0.50)

0.90

Day 0 hematocrit

0.37 (0.31–0.45)

0.36 (0.30–0.43)

0.37 (0.32–0.46)

0.92

Day 2 hematocrit

0.30 (0.30–0.40)

0.32 (0.26–0.41)

0.33 (0.28–0.40)

0.09

Day 5 hematocrit

0.30 (0.20–0.40)

0.32 (0.26–0.38)

0.32 (0.24–0.39)

0.22

Drain output (ml)

398.80 (100–1000)

313.80 (70–990)

304.60 (50–1070)

0.03

Calculated blood loss (ml)

886.70 (332–1662)

809.21 (437–1944)

790.01 (251–1536)

0.24

Calculated + unadjusted blood loss (ml)

918.60 (332–1662)

810.74 (437–1944)

790.01 (251–1536)

0.07

Transfusion

4

0

1

0.13

Doppler ultrasound

8

6

2

0.23

Deep vein thrombosis

1

2

0

0.77

Complication

Acute coronary syndrome, early infection

Hematoma evacuation

 
  1. Keys:
  2. IA Intra-arterial
  3. IV Intra-venous
  4. ASA American Society of Anesthesiologists
  5. BMI Bone mineral density
  6. #: P values calculated using one-way ANOVA