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Table 1 Baseline demographics of the patients and information on blood transfusions

From: Prospective randomized trial comparing efficacy and safety of intravenous and intra-articular tranexamic acid in total knee arthroplasty

Covariates Group A (IA 20 mg/kg)
(N = 50)
Group B (IA 2 g/kg)
(N = 50)
Group C (IV 20 mg/kg)
(N = 50)
P value#
Age 67.40 (50–79) 65.82 (54–83) 66.58 (50–81) 0.40
Sex (male:female) 13:37 7:43 14:36 0.22
Side (left:right) 26:24 23:27 26:24 0.86
Height (cm) 154.97 (145–174) 154.44 (138–172) 156.02 (142–171) 0.89
Weight (kg) 68.20 (53–98) 67.76 (54–95) 68.13 (48–99) 0.96
BMI (kg/m2) 28.42 (21–40) 28.36 (22–37) 27.99 (20–42) 0.83
ASA 3:37:9 10:34:4 8:37:4 0.15
Length of stay (days) 8.88 (4–34) 7.96 (5–15) 8.70 (5–45) 0.53
Baseline hemoglobin (g/dL) 13.73 (12–16) 13.39 (12–15) 13.41 (12–17) 0.17
Day 0 hemoglobin (g/dL) 12.27 (10–15) 12.06 (10–14) 12.17 (10–15) 0.78
Day 2 hemoglobin (g/dL) 10.60 (8–15) 10.61 (9–14) 10.73 (9–13) 0.74
Day 5 hemoglobin (g/dL) 10.59 (8–13) 10.57 (9–13) 10.69 (8–13) 0.76
Baseline platelet 236.62 (132–378) 225.50 (129–335) 241.68 (137–379) 0.34
Day 0 platelet 212.28 (108–348) 201.28 (111–314) 218.34 (121–339) 0.20
Day 2 platelet 184.04 (109–303) 173.42 (103–291) 193.22 (110–397) 0.11
Day 5 platelet 275.64 (155–458) 263.76 (144–408) 282.62 (162–519) 0.34
Baseline hematocrit 0.41 (0.36–0.48) 0.40 (0.36–0.46) 0.41 (0.36–0.50) 0.90
Day 0 hematocrit 0.37 (0.31–0.45) 0.36 (0.30–0.43) 0.37 (0.32–0.46) 0.92
Day 2 hematocrit 0.30 (0.30–0.40) 0.32 (0.26–0.41) 0.33 (0.28–0.40) 0.09
Day 5 hematocrit 0.30 (0.20–0.40) 0.32 (0.26–0.38) 0.32 (0.24–0.39) 0.22
Drain output (ml) 398.80 (100–1000) 313.80 (70–990) 304.60 (50–1070) 0.03
Calculated blood loss (ml) 886.70 (332–1662) 809.21 (437–1944) 790.01 (251–1536) 0.24
Calculated + unadjusted blood loss (ml) 918.60 (332–1662) 810.74 (437–1944) 790.01 (251–1536) 0.07
Transfusion 4 0 1 0.13
Doppler ultrasound 8 6 2 0.23
Deep vein thrombosis 1 2 0 0.77
Complication Acute coronary syndrome, early infection Hematoma evacuation  
  1. Keys:
  2. IA Intra-arterial
  3. IV Intra-venous
  4. ASA American Society of Anesthesiologists
  5. BMI Bone mineral density
  6. #: P values calculated using one-way ANOVA