Table 1 Univariate analysis of demographic and comorbidity variables for deep vein thrombosis, pulmonary embolism, and all-cause venous thromboembolic disease
DVT | PE | VTED | ||||
|---|---|---|---|---|---|---|
N (%) | P value | N (%) | P value | N (%) | P value | |
Age (years) | ||||||
18–54 (N = 23,636) | 192 (0.8%) | < 0.001a | 103 (0.4%) | < 0.001 | 274 (1.2%) | < 0.001 |
55–75 (N = 143,972) | 1182 (0.8%) | 815 (0.6%) | 1858 (1.3%) | |||
> 75 (N = 45,626) | 471 (1.0%) | 323 (0.7%) | 722 (1.6%) | |||
Body mass index (kg/m2) | ||||||
< 25 (N = 21,699) | 189 (0.9%) | 0.101 | 75 (0.3%) | < 0.001 | 244 (1.1%) | 0.023 |
25–34.99 (N = 119,669) | 1083 (0.9%) | 681 (0.6%) | 1638 (1.4%) | |||
35–44.99 (N = 60,374) | 485 (0.8%) | 419 (0.7%) | 828 (1.4%) | |||
45+ (N = 11,492) | 88 (0.8%) | 66 (0.6%) | 144 (1.3%) | |||
Sex | ||||||
Male (N = 82,759) | 743 (0.9%) | 0.203 | 421 (0.5%) | < 0.001 | 1090 (1.3%) | 0.498 |
Female (N = 130,475) | 1102 (0.8%) | 820 (0.6%) | 1764 (1.4%) | |||
History of smoking (N = 18,142) | 160 (0.9%) | 0.806 | 897 (0.5%) | 0.062 | 229 (1.3%) | 0.362 |
History of diabetes mellitus (N = 37,948) | 289 (0.8%) | 0.016 | 224 (0.6%) | 0.826 | 486 (1.3%) | 0.290 |
Anesthesia type | ||||||
Regional (N = 107,001) | 862 (0.8%) | 0.003 | 641 (0.6%) | 0.319 | 1387 (1.3%) | 0.083 |
General (N = 105,931) | 982 (0.9%) | 599 (0.6%) | 1465 (1.3%) | |||
ASA class | ||||||
Class 1 (N = 4231) | 40 (0.9%) | 0.337 | 14 (0.3%) | 0.075 | 51 (1.2%) | 0.097 |
Class 2 (N = 106,509) | 884 (0.8%) | 600 (0.6%) | 1366 (1.3%) | |||
Class 3 (N = 99,006) | 892 (0.9%) | 607 (0.6%) | 1390 (1.4%) | |||
Class 4 (N = 3488) | 29 (0.8%) | 20 (0.6%) | 47 (1.3%) | |||
Operative time (hours) | ||||||
< 2 (N = 172,154) | 1467 (0.9%) | 0.406 | 992 (0.6%) | 0.066 | 2270 (1.3%) | 0.117 |
2–4 (N = 33,384) | 308 (0.9%) | 189 (0.6%) | 463 (1.4%) | |||
> 4 (N = 7696) | 70 (0.9%) | 60 (0.8%) | 121 (1.6%) | |||
Arthroplasty type | ||||||
Primary total Knee arthroplasty (N = 191,810) | 1706 (0.9%) | < 0.001 | 1169 (0.6%) | < 0.001 | 2655 (1.4%) | < 0.001 |
Unicompartmental knee arthroplasty (N = 9294) | 36 (0.4%) | 22 (0.2%) | 52 (0.6%) | |||
Revision total knee arthroplasty (N = 12,130) | 103 (0.8%) | 50 (0.4%) | 147 (1.2%) | |||