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Table 2 Methods used to calculate minimal clinically important difference

From: Minimal clinically important difference of commonly used patient-reported outcome measures in total knee arthroplasty: review of terminologies, methods and proposed values

CitationTestMethodAnchor questionTransitional scale
Quintana et al., 2006 [16]WOMAC and SF-36Mean changeNot specified5-point scale
Escobar et al., 2007 [14]WOMAC and SF-36Mean changeNot specified5-point scale
Chesworth et al., 2008 [13]WOMAC*ROC“Compared to when they went on the wait list for surgery, they were better, worse or the same”15-point scale
Escobar et al., 2013 [17]WOMAC*Mean change
ROC
“Compared to before surgery, how would you rate pain (functional limitation) in the same knee?”
“Was surgery worthwhile?”
“What is your global level of satisfaction with surgical management?”
5-point scale
Clement et al., 2014 [18]OKS and SF-12 PCSLinear regression analysis“How well did the surgery relieve pain in your affected joint?”
“How well did the surgery increase your ability to perform regular activities?”
5-point scale
Escobar et al., 2014 [15]WOMAC*Mean changeNot specified5-point scale
Maratt et al., 2015 [12]WOMAC*ROC“How much did your knee surgery improve the quality of your life?6-point scale
Beard et al., 2015 [28]OKSMean difference
Mean change and ROC
“Overall, how are your problems now, compared to before your operation?”5-point scale
Lee et al., 2017 [21]KSSLinear regression analysisHow would you rate the overall results of the surgery for your knee condition?”6-point scale
Ingelsrud et al., 2018 [29]OKSMean change
Logistic regression and ROC
“How are your knee problems now compared to prior to operation?”7-point scale
Lizaur-Utrilla et al., 2019 [23]KSSMean difference
ROC and 0.5 SD
“Compared to before surgery, how would you rate the pain in your knee and the ability to perform regular activities now?5-point scale
Clement et al., 2019 [25]SF-12Mean difference
ROC
“How much did the knee replacement surgery improve the quality of your life?”5-point scale
Kiran et al., 2014 [19]OKS0.5 SDDistribution-based method
Keurentjes et al. 2014 [26]SF-360.8 SDDistribution-based method
Kiran, et al., 2015 [27]OKS0.5 SDDistribution-based method
Bin Abd Razak et al., 2016 [20]OKS and SF-36 PCS0.5 SDDistribution-based method
Berliner, et al., 2017 [22]SF-12 PCS0.5 SDDistribution-based method
Blevins et al., 2019 [24]SF-120.5 SDDistribution-based method
  1. MCID minimal clinically important difference, TKA total knee arthroplasty, PROM patient-reported outcome measures, WOMAC Western Ontario And McMaster University Arthritis Index, WOMAC* Western Ontario and McMaster University Arthritis Index reversed scoring system, OKS Oxford Knee Score, KSS Knee Society Score, SF-36 36-item Short Form survey, PCS physical component summary, SF-12 12-item Short Form Survey, ROC receiver operator characteristics, 0.5 SD half of a standard deviation, , 0.8 SD four fifths of a standard deviation